Biolinx polymer
WebKeywords: BioLinx, clinical outcomes, drug-eluting stent, phoshorylcholine, Polymer, Zotarolimus Editor: Leonardo Roever. YHK and A-YH contributed equally to the writing of this article. WebBioLinx ® is comprised of a blend of three different polymers: a 95/5 butyl methacrylate–vinyl acetate copolymer, 77/18/5 hexyl methacrylate-vinyl pyrrolidinone-vinyl acetate terpolymer and polyvinyl pyrrolidinone. The BioLinx ® polymer system was designed to exhibit similar, predominantly hydrophilic properties as Endeavor ® 's PC …
Biolinx polymer
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WebApr 1, 2014 · The 5.6-μm-thick BioLinx polymer system, which covers the entire stent platform, elutes zotarolimus as the antiproliferative agent. The polymer system consists … WebOct 25, 2006 · The polymers on some drug-eluting stents can produce an inflammatory response within the blood vessel, which can lead to thrombosis and occlusion of the artery. This is more pronounced in patients with complex medical conditions. BioLinx is a non-inflammatory polymer blend that mimics the make-up of a cell membrane to maintain …
WebWhereas the stent, the drug and the delivery system are all important components of the DES system, polymer coatings control local delivery of drugs. The first generation DES are based on biostable polymers that remain in the body well after the drug is exhausted, and if the polymers are not biocompatible, they can elicit inflammatory response. WebWaseda et al15 investigated the effect of polymer formu-lations on neointimal proliferation after ZES implantation. At follow-up, intravascular ultrasound-determined percent neo-intimal obstruction was significantly lower in Resolute ZES (BioLinx polymer—slow drug-release kinetic), compared with Endeavor and ZoMaxx ZES (phosphorylcholine ...
WebMay 28, 2007 · 이 임상연구에 사용된 제품은 메드트로닉 엔데버 레졸루트(Endeavor Resolute) 약물방출스텐트로 새로운 바이오링스(BioLinx) 폴리머를 사용하여 복합적인 질환으로 더 긴 치유기간을 요구하는 환자들을 위해 설계된 차세대 약물방출스텐트이다. WebThe BioLinx polymer is designed to confer the same biocompatibility as the Endeavor stent’s phosphorylcholine (PC) polymer while extending the duration of drug exposure in the vessel. Developed by Medtronic …
WebBioLineRx is committed to the identification, in-licensing and systematic development of promising therapeutic candidates. Through this strategy, BioLineRx is building a pipeline of powerful technologies in oncology. …
WebThere are limited long-term outcome data comparing BioLinx polymer (B)-zotarolimus-eluting stents (ZES) with phosphorylcholine polymer (P)-ZES.The aim of this study was to compare the efficacy and safety of B-ZES with P-ZES in patients who underwent percutaneous coronary intervention (PCI) during a 3-year follow-up period. homewood ocalaWebWe have also applied this methodology to evaluate the components of a novel polymer system (BioLinx polymer system) designed in-house. In addition, we assayed other polymeric coatings similar to those currently used on various DES. The results of this evaluation reveal a remarkable correlation between polymer hydrophobicity and its … homewood offersWebWhereas the stent, the drug and the delivery system are all important components of the DES system, polymer coatings control local delivery of drugs. The first generation DES … homewood nursing home williamsport mdWebThe next generation Endeavor Resolute Stent: role of the BioLinx Polymer System EuroIntervention. 2007 May;3(1):137-9. Authors Kishore Udipi 1 , Robert J Melder, … homewood officeWebMar 10, 2024 · The BioLinx polymer or its individual components Coronary artery stenting should not be used for people who: Cannot have anti-platelet and/or anticoagulation … homewood nutritionWebJul 19, 2011 · Zotarolimus-eluting stent with biolinx polymer (ZES, Endeavor Resolute or Endeavor Resolute Intergrity, Medtronic, USA) has DRIVER stent platform. The durable polymer in this DES has changed from phosphorylcholine (PC) polymer which was used in Endeavor to Biolinx polymer which has more biocompatible features. homewood of crumland farms frederick mdWebThe zotarolimus drug inhibits neointimal growth 10 while the BioLinx biocompatible polymer — the only polymer specifically designed for a DES — promotes faster … homewood officer injured