Chemical induction of apoptosis zebrafish
WebDec 24, 2009 · Apoptosis plays important roles in embryogenesis, tissue homeostasis, and immune system regulation. The zebrafish (Danio rerio) is a powerful vertebrate model organism that has been extensively used to study apoptotic cell death during normal development and under conditions of cellular stress. In the past 5 years, a detailed … WebDec 14, 2024 · The results indicate that SCIP inhibits the growth of MCF-7 tumor cells in zebrafish and increases the apoptosis of human breast cancer MCF-7 cells. ... Bax is the protein acting contrary role to bcl-2 in the process of apoptosis. When Bax forms a homologous dimer, the induction of apoptosis increases. ... Wen J, Hu C, Fan S. …
Chemical induction of apoptosis zebrafish
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WebJul 1, 2024 · Zebrafish embryos were exposed to 50, 100 and 200 µM of AlCl 3 for 72 h. • Aluminium (Al) exposure induced teratogenic effects on zebrafish larvae. • Apoptosis … WebAug 8, 2024 · DNA damage, apoptosis and histopathological alterations on zebrafish exposed with green silver nanoparticle, Chemistry and Ecology, 38:7, 655-670, DOI: 10.1080/02757540.2024.2108808
WebExposure to PRW-SeNPs significantly inhibited the growth of A549 cells through induction of apoptosis and G2/M phase arrest ... Structure features and evaluation of anti-tumor activity in zebrafish models. Carbohydrate Polymers 2024, 270 , 118365. ... Chemical Modifications and Biological Activity. Applied Sciences 2024, 11 (8) , 3717. WebMar 17, 2024 · Chemical induction of zebrafish models is generally achieved by exposing embryos to a relevant molecule through the incubation medium (Martin et al., 2024, Powers et al., 2024, Roy et al., 2024, Morrice et al., 2024, Wang et …
WebAug 13, 2024 · In general, apoptosis can be induced either by an extrinsic pathway mediated through the activation of death receptors or by an intrinsic signalling pathway, which involves in the alteration of... WebNov 15, 2016 · This shows that the induction of apoptosis is fast occurring synchronously within a few hours. The low percentage of PCs containing activated Caspase 3 compared with widespread fragmentation of the PC layer after 16 h of 4OHT treatment suggests that activated Caspase 3 staining is only transient in dying PCs.
WebGenotoxicity is the ability of specific substances to cause DNA damage, affecting development, physiology, and reproduction. This is often mediated by induction of …
WebSulfamethoxazole (SMX) is a broad-range bacteriostatic antibiotic widely used in animal and fish farming and is also employed in human medicine. These antibiotics can ultimately end up in the aquatic ecosystem and affect non-target organisms such as lease auto bad creditWebDec 20, 2024 · Low concentration of arsenate can induce apoptosis of zebrafish larvae stage via the mitochondrial pathway. 1. Introduction Arsenic (As) is a ubiquitous metallic element in the environment, which is eventually discharged into the water due to natural and anthropogenic activities, resulting in As contamination in water. lease auto belastingWebDec 1, 2003 · Induction of apoptosis in vivo can be detected by assaying caspase activity using Ac-DEVD-MCA and terminal deoxynucleotidyl dUTP nick end-labeling … lease auto body shopWebSep 1, 2002 · Another key finding was that a caspase inhibitor abolished apoptosis in the dorsal midbrain of the zebrafish without a reduction in blood flow in the mesencephalic vein. The authors conclude that circulatory failure and oxidative stress in the vascular endothelium are primary events in dioxin-induced toxicity, while the apoptosis in the neural ... lease auto en hypotheekWebIn the present study, we investigated the effects of CYP exposure on the induction of apoptosis and immunotoxicity in zebrafish during the embryo developmental stage. The … how to do rollups in excelWebMar 18, 2024 · Wnt/β-catenin signaling is also stimulated by apoptosis in zebrafish epithelium regeneration ( Brock et al., 2024 ). In both systems, the Wnt ligand is found in apoptotic bodies and engulfed by neighboring stem cells to induce proliferation. how to do roll up the rimWebApoptosis inducers act on several apoptosis-related proteins to promote apoptotic cell death. Depending on the agent selected and the concentrations used, apoptotic events can be detected between 8–72 h post-treatment. However, not all reagents will affect a … how to do roman deadlift